| Date | Country | Change |
| 1916 | Metropolitan Archdiocese of Benevento lost territory to Diocese of Lucera | |
| 1916 | Diocese of Larino lost territory to Diocese of San Severo | |
| 1916 | Titular Episcopal See of Ostroh was suppressed | |
| 1916.01.07 | Apostolic Vicariate of Temiskaming was promoted as Diocese of Haileybury | |
| 1916.02.02 | Diocese of Comayagua was suppressed (to establish Metropolitan Archdiocese of Tegucigalpa, Diocese of Santa Rosa de Copán and Apostolic Vicariate of San Pedro Sula) | |
| 1916.02.02 | Apostolic Vicariate of San Pedro Sula was established (from the suppressed Diocese of Comayagua and became suffragan of Tegucigalpa) | |
| 1916.02.02 | Diocese of Santa Rosa de Copán was established (from the suppressed Diocese of Comayagua and became suffragan of Tegucigalpa) | |
| 1916.02.02 | Metropolitan Archdiocese of Tegucigalpa was established (from the suppressed Diocese of Comayagua and with suffragan sees Santa Rosa de Copán and San Pedro Sula) | |
| 1916.02.03 | Diocese of Guaxupé was established (from Diocese of Pouso Alegre and became suffragan of Mariana) | |
| 1916.02.07 | Diocese of Newport was suppressed (to establish Metropolitan Archdiocese of Cardiff) | |
| 1916.02.07 | Metropolitan Archdiocese of Cardiff was restored (from the suppressed Diocese of Newport and with suffragan see Menevia) | |
| 1916.04.03 | Diocese of Penedo was established (from Diocese of Alagôas and became suffragan of Olinda) | |
| 1916.09 | Metropolitan Archdiocese of Firenze lost territory to Diocese of Prato | |
| 1916.09 | Diocese of Pistoia lost territory to Diocese of Prato | |
| 1916.09.21 | Apostolic Vicariate of Eastern Honan 河南東境 was established (from Apostolic Vicariate of Northern Honan 河南北境 and Apostolic Vicariate of Southern Honan 河南南境) | |
| 1916.10.04 | Apostolic Prefecture of Patagonia Meridional, Tierra del Fuego e Islas Malvinas was promoted as Apostolic Vicariate of Magallanes y Islas Malvinas (became suffragan of Santiago) | |
| 1916.11.20 | Metropolitan Archdiocese of Vancouver lost territory to Apostolic Vicariate of Yukon–Prince Rupert | |
| 1916.11.20 | Apostolic Prefecture of Yukon was promoted as Apostolic Vicariate of Yukon–Prince Rupert (gained territory from Metropolitan Archdiocese of Vancouver) |
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