| Date | Country | Change |
| 1942 | Titular Episcopal See of Mundinitza was renamed as Titular Episcopal See of Mundinitza | |
| 1942 | Titular Episcopal See of Orthosias in Phœnicia was renamed as Titular Episcopal See of Orthosia in Phœnicia | |
| 1942 | Titular Episcopal See of Tanais was renamed as Titular Episcopal See of Tanais | |
| 1942.03.08 | Diocese of Leopoldina was established (from Metropolitan Archdiocese of Mariana and Diocese of Juiz de Fora and became suffragan of Mariana) | |
| 1942.04.28 | Apostolic Prefecture of Niamey was established (from Apostolic Vicariate of Dahomey, Apostolic Vicariate of Foumban, Apostolic Vicariate of Khartoum, Apostolic Vicariate of Ouagadougou, Apostolic Prefecture of Ghardaïa nel Sahara, Apostolic Prefecture of Jos and Apostolic Prefecture of Kaduna) | |
| 1942.04.29 | Apostolic Vicariate of Pando was established (from Apostolic Vicariate of El Beni) | |
| 1942.06.09 | Apostolic Prefecture of Fengxiangfu 鳳翔府 was promoted as Apostolic Vicariate of Fengxiangfu 鳳翔府 | |
| 1942.06.09 | Apostolic Prefecture of Gao was established (from Apostolic Vicariate of Bamako, Apostolic Vicariate of Bobo-Dioulasso and Apostolic Vicariate of Ouagadougou) | |
| 1942.06.30 | Territorial Abbacy of San Paolo fuori le Mura lost territory to Diocese of Amelia | |
| 1942.09.01 | Apostolic Vicariate of Reyes was established (from Apostolic Vicariate of El Beni) |
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